Las Vegas was an American city in the state of Nevada. Las Vegas' economy was driven by tourism, primarily to the Las Vegas Strip, home to numerous casinos and other attactions.
The Counter Terrorist Unit operated a domestic unit, CTU Las Vegas, within the city.
A Chinese splinter group attempted to attack Las Vegas using Groom Lake Air Force Base's newly developed Malignant Wave bioweapon. (Vanishing Point)
Lynne Kresge reported that detonating Second Wave's nuclear bomb in the Mojave Desert could result in some radioactive fallout blowing into Las Vegas, but said that under the current wind conditions it would be unlikely. ("Day 2: 10:00pm-11:00pm")
Las Vegas was one of the cities threatened with the release of the Cordilla virus by Stephen Saunders. Federal agents in Las Vegas managed to apprehend the courier before the virus could be released. ("Day 3: 11:00am-12:00pm")
CTU Las Vegas personnel assisted in the search and rescue of President John Keeler, who had been grievously injured aboard Air Force One when it crashed in the desert outside the city on Day 4. ("Day 4: 11:00pm-12:00am")
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