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For the most part, the series closely hews to the plot of the American series, substituting Mumbai for Los Angeles and featuring the fictional Anti Terrorist Unit. There are a number of significant changes from the American series:
Names, places, and nationalities are adjusted to reflect the new setting. The primary antagonists are members of a Tamil separatist group called the LTFE, inspired by the real-life Liberation Tigers of Tamil Eelam (LTTE for short, commonly referred to as the "Tamil Tigers") in Sri Lanka. The LTFE leader, Ravindran, and his sons Raja and Bala play a similar role as Victor Drazen and his sons in the original first season.
The political story arc, which followed David Palmer discovering a cover-up perpetrated by his own wife and children, is entirely rewritten; Singhania is unmarried, and instead contends with a scandal involving his mother and siblings that is directly connected to the threat against his life. Over the course of the season, it is revealed that Aditya's brother-in-law, as well as one of his family members - his mother, cousin Prithvi, or sister Divya - is in league with the masterminds of the assassination attempt. In the finale, Divya is exposed as the inside connection and arrested.
Aditya has only one press secretary, Pooja, who appears to have parts of Patty Brooks, Elizabeth Nash and Jessica Abrams written into her role- but unlike Patty, she does not spy or have feelings for Aditya, and like Elizabeth, was secretly seeing Bala (the Alexis Drazen role equivalent).
The journalist Mehek Ahuja, based on Maureen Kingsley, also has elements of Dr George Ferragamo, being in touch longer with the Singhania family (one of whom was her source of the story), and actively trying to push the story, although her motivation is different- and eventually getting killed before coming on air with the story.
The Jonathan Matijevich character has no name, even in credits, and a longer role to play, beyond the first attempt on Aditya's life. He then attempts to kill Trisha and Kiran in the safehouse. He also does most of the work otherwise done by Jovan Myovic, whose counterpart appears briefly in only two episodes, one being the final.
The Nina Myers character, Nikita Rai, is not revealed to be an enemy agent, instead serving loyally throughout the season. She does not return in the second season and nothing is known about her whereabouts or present status. The Jamey Farrell character, Jiah, is the only mole inside ATU, and takes her own life after being arrested.
This show does not have a character directly based on Mike Novick, as a result of the structure and background of Aditya's family and associates being changed so heavily. Much of his work is initially done by Prithvi, Aditya's cousin, with an original character, CBI Agent Bhagwat, to carry forward his work later on.
The make-up and outcome of Jack Bauer's family are altered. Rathod has a teenage son, Veer, enrolled at a military academy, in addition to a daughter. Beginning in "Day 1: 3:00pm-4:00pm," the family's story begins to diverge from the original - Trisha and Kiran manage to kill the assassin sent to kill them at the safe house, while Veer assumes a similar role to Kim Bauer in the latter half of Season 1, being mistakenly arrested for a drug deal and then kidnapped by the engineers of the assassination threat.
Rathod's wife, Trisha, is hospitalized late in the season and dies during the season finale, mirroring Teri Bauer's death at the end of Season 1.
Jai gets an urgent call for help from Wassim Khan, who is under fire from assassins. Mehr and her sister pass the security card to Yakub, but demand more money. Trisha gets a clue on Kiran's location, but Kiran's situation becomes more dangerous.
Jai makes it to the hospital to meet Trisha and Abhay. Rohit and Kiran realise they are both prisoners of Yakub Syed, and Yakub makes contact with Jai. Nikita works to identify a dead body, while Aditya resolves to address his allegations head on.
Aditya Singhania prepares for damage control after the news of his survival is leaked to the press. Jai Singh Rathod confronts Ravindran and Raja and rescues his son. A second assassination attempt is foiled, and the true mastermind is revealed, but Trisha does not make it through the day.