James brought up the story of his grief following Susan's death in an attempt to comfort Erin Driscoll, who was beginning to mourn the suicide of her daughter Maya Driscoll during Day 4:
When my wife Susan died, I didn't deal with it at all. Actually, I went to work the next day. I remember thinking to myself, that's life. Quit feeling sorry for yourself. Get over it and get on with it. A few weeks later, I answered a call from an old friend of Susan's who did not know she had died. And when I heard myself saying, "Susan has passed away," when I actually said those words, it hit me. All the pain I was trying to shut out just overwhelmed me. Erin, you can't keep it inside. You cry, you blame God, you blame yourself and then you cry some more. And all the while you let you friends help you. It's pretty simple. Very painful. And I am so, so sorry for you.
Upon Susan's first mention in "Day 4: 6:00pm-7:00pm," she was confirmed as James Heller's wife, yet only assumed to be the mother of Heller's children. During "Day 6: 1:00am-2:00am" Jack Bauer attempts to shock Audrey out of a catatonic state by reminding her of her name, place of birth, and that her mother's name was "Alicia". Bauer mentions that Alicia died when Audrey was nine years old. This may be a continuity error. In-universe, it is not established if Alicia and Susan were different names for the same person, or separate wives/partners of James. While Alicia was definitely Audrey's mother, it is unclear if she was also the mother of James Heller's son, Richard.